Dr. Doreen Matsui, MD, FRCPC


Children’s Health Research Institute
Scientist, Children’s Optimal Therapeutics Program


Lawson Health Research Institute
Associate Scientist, Children’s Health Research Institute


Children’s Hospital of Western Ontario
Consultant, Clinical Pharmacology


University of Western Ontario
Associate Professor, Departments of Paediatrics and Medicine


Contact Information
Tel: (519) 685-8500 Ext. 58268
Fax: (519) 685-8156
E-mail: Doreen.matsui@lhsc.on.ca


Brief Biography

Dr. Doreen Matsui received her Degree in Medicine from Queen’s University in 1985. She completed a residency in paediatrics at the Children’s Hospital of Eastern Ontario, University of Ottawa and a fellowship in paediatric clinical pharmacology at the Hospital for Sick Children, University of Toronto. She also received a Certificate in Clinical Epidemiology from The University of Western Ontario in 2002.


Dr. Matsui joined the Schulich School of Medicine at The University of Western Ontario in 1993, and is a paediatrician and clinical pharmacologist at the Children’s Hospital of Western Ontario. She is an Associate Professor in the Departments of Paediatrics and Medicine. She currently is a member of the Review Board for Health Sciences Research Involving Human Subjects at The University of Western Ontario and Chair of the Drug Therapy and Hazardous Substances Committee of the Canadian Paediatric Society.


Research Interests

• Drug therapy in children, medication compliance and the effects of drugs in pregnancy


Research Activities

Dr. Matsui’s research interests include drug therapy in children, medication compliance and the effects of drugs in pregnancy. She was awarded the K.M Piafsky Young Investigator Award of the Canadian Society for Clinical Pharmacology in 1998.


Representative Publications

  1. Jayaraman S, Rieder MJ, Matsui D (2005). Compliance Assessment in Drug Trials: Has there been improvement in two decades? Can J Clin Pharmacol e251-e253.
  2. Koren G, Matsui D, Einarson A, Knoppert D, Steiner M (2005). Is maternal use of selective sertonin reuptake inhibitors in the third trimester of pregnancy harmful to neonates? CMAJ 172:1457-9
  3. Matsui D (2005). Adherence. In: Osborn, Dewitt, First, Zenel, eds. Pediatrics, 1st edition. Philadelphia: Elsevier Mosby; p. 1782-4.
  4. Matsui D, Kwan C, Steer E, Rieder MJ (2003). The trials and tribulations of doing drug research in children. CMAJ 169:1033-4.
  5. Koren G, Matsui D, Bailey B (2003). DEET-based insect repellents: safety implications for children and pregnant and lactating women. CMAJ 169:209-12.
  6. Matsui D, Jardine M, Steer E, Cukernik V, Rieder MJ (2003). Where physicians look for information on drug prescribing for children. Paediatr Child Health 8:219-21.
  7. Matsui D, Joubert GIE, Dykxhoorn S, Rieder MJ (2000). Compliance with Prescription Filling in the Pediatric Emergency Department. Arch Pediatr Adolesc Med 154:195-8.
  8. Cho M, Matsui D, Rieder MJ (1998). Physicians' attire as perceived by young children and their parents: The myth of the white coat syndrome. Pediatr Emerg Care 14:198-201.
  9. Matsui D, Lim R, Tschen T, Rieder MJ (1997). Assessment of the Palatability of ß-lactamase-Resistant Antibiotics in Children. Arch Pediatr Adolesc Med 151:599-602.
  10. Matsui D (1997). Drug Compliance in Pediatrics: Clinical and Research Issues. Pediatr Clin North Am 44:1-14.