Doreen Matsui

Children's Health & Therapeutics Dr. Doreen Matsui
Associate Scientist


Scientist, Division of Children’s Health and Therapeutics, Children’s Health Research Institute
Associate Professor, Departments of Paediatrics and Medicine, Schulich School of Medicine & Dentistry,
Western University

How my research helps children

Use of medications in children is common. My research helps children by looking at improving the drug treatment of diseases in children by looking at how well the medications work, if they are safe to take and what effects whether they take their medications or not. Pregnant women often avoid medications as they are afraid that they will harm their unborn child. By looking at the effects of drugs taken during pregnancy, the information obtained may help pregnant women make a more informed decision regarding their drug therapy and reduce anxiety.


Current Research Activities

My research interests include drug therapy in children, medication adherence and the effects of drugs in pregnancy and lactation. I am a member of the Research Ethics Board for Health Sciences Research Involving Human Subjects at the University of Western Ontario. I am involved in the research education of paediatric residents chairing the Resident Research Subcommittee Committee in the Department of Paediatrics.


Future Research Plans

I hope to continue to develop my research interests in medication adherence in children and the effects of drugs in pregnancy. I would also like to further explore the area of research ethics in children.

Recent Publications


Diagnosis and management of poor neonatal adaptation syndrome in newborns exposed in utero to selective seretonin/norepinephrine reuptake inhibitors
Koren G, Finkelstein Y, Matsui D, Berkovich M
J Obstet Gynaecol Can. 2009 Apr;31(4):348-50

Safety of 14C-UBT for diagnosis of Helicobacter pylori infection in pregnancy
Bentur Y, Matsui D, Koren G
Can Fam Physician. 2009 May;55(5):479-80

A needs assessment for obesity-related anticipatory guidance in the paediatric emergency department
Warkentin J, Chan M, Igric A, Seabrook JA, Matsui D, Lim R, Joubert G
Paediatr Child Health. 2008 Nov;13(9):769-71

Pregnancy outcome following in utero exposure to bisphosphonates
Levy S, Fayez I, Taguchi N, Han JY, Aiello J, Matsui D, Moretti M, Koren G, Ito S
Bone. 2009 Mar;44(3):428-30

What is the risk of using a cephalosporin in a patient with a penicillin allergy?
Cormier A, Rieder MJ, Matsui D
Paediatr Child Health. 2007 May;12(5):387-8

Rural women and pharmacologic therapy: needs and issues in rural Canada
Leipert BD, Matsui D, Wagner J, Rieder MJ
Can J Rural Med. 2008 Autumn;13(4):171-9

MotherNature: establishing a Canadian research network for natural health products (NHPs) during pregnancy and lactation
Koren G, Dugoua JJ, Magee L, Vohra S, Matsui D, Bérard A, Johnson B, Moretti M, Einarson A
J Altern Complement Med. 2008 May;14(4):369-72

Elective tracheostomy in mechanically ventilated children in Canada
Principi T, Morrison GC, Matsui DM, Speechley KN, Seabrook JA, Singh RN, Kornecki A
Intensive Care Med. 2008 Aug;34(8):1498-502

A palatability study of a flavored dexamethasone preparation versus prednisolone liquid in children
Hames H, Seabrook JA, Matsui D, Rieder MJ, Joubert GI
Can J Clin Pharmacol. 2008 Winter;15(1):e95-8

Current issues in pediatric medication adherence
Matsui D
Paediatr Drugs. 2007;9(5):283

Additional publications



Phone: (519) 685-8500, x58268
Fax: (519) 685-8156
Email: doreen [dot] matsui [at] lhsc [dot] on [dot] ca or dmatsui [at] uwo [dot] ca

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