Dr. Robert Gagnon, MD, FRCSC
Children’s Health Research Institute
Scientist, Fetal and Newborn Health Program
Lawson Health Research Institute
Scientist, Children’s Health Research Institute
University of Western Ontario
Professor, Departments of Obstetrics and Gynaecology, Physiology &
Pharmacology, and Paediatrics
Professor, Faculty of Graduate Studies
Other Appointments
Chair, Maternal Fetal Medicine Division, Department of Obstetrics and
Gynaecology, University of Western Ontario
Chair, Maternal Fetal Medicine Nucleus Committee, Royal College of Physicians
and Surgeons of Canada
Chair, Subspecialties Committee, Association of Professors of Obstetrics
and Gynaecology of Canada (APOG)
Contact Information
Tel: (519) 646-6106
Fax: (519) 646-6213
E-mail: rgagnon@uwo.ca
Brief Biography
Dr. Gagnon received his medical degree in 1980 from the University of
Montreal, and continued his training in Obstetrics and Gynaecology in
the University of Montreal. He then received research training in the
laboratories of the MRC Group in Reproductive Biology – Fetal Physiology
under the supervision of Professor John Patrick at The University of Western
Ontario.
Dr. Gagnon was appointed as an Assistant Professor in the Department
of Obstetrics and Gynaecology at The University of Western Ontario in
1987. He then became an Associate Professor in the Departments of Obstetrics
and Gynaecology and Physiology & Pharmacology in 1993, and was promoted
to full Professor in 1998.
Research Interests
• Placental insufficiency
• Diagnostic indicators of fetal health
• Fetal cardiovascular physiology
Research Activities
Dr. Gagnon’s research interests are of placental insufficiency
and its effect on fetal growth and development. His laboratory has established
a chronic fetal sheep model of placental insufficiency producing an increase
in placental vascular resistance in addition to fetal hypoxemia.
He is
also conducting large epidemiological studies to determine the effect
of placental insufficiency on fetal and neonatal outcome in humans. He
has published 66 peer reviewed medical articles, 25 book chapters and
151 scientific abstracts. He has supervised 14 research trainees, including
medical students, obstetrics and gynaecology residents, perinatal research
fellows and graduate as well as postgraduate trainees.
Representative Publications
- Dervaitis KL, Poole M, Schmidt G, Penava D, Natale R, Gagnon R (2004).
ST segment analysis of the fetal electrocardiogram plus electronic fetal
heart rate monitoring in labor and its relationship to umbilical cord
arterial blood gases. Am J Obstet Gynecol 191(3):879-884.
- Cheung CY, Bogic L, Gagnon R, Harding R, and Brace RA (2004). Morphological
alterations in ovine placenta and fetal liver following induced severe
placental insufficiency. Journal of the Society for Gynecological Investigation
11(8):521-528.
- Zaw Win, Gagnon R, daSilva Orlando (2003). The risk of adverse neonatal
outcome among preterm small for gestational age infants according to neonatal
versus fetal growth standards. Pediatrics Jun;111(6 Pt 1):1273-7.
- Gagnon R (2003). Placental insufficiency and its consequences. European
Journal of Obstetrics and Gynecology Sept 22;110 Suppl 1:S99-107.
- Gagnon R, Harding R, Brace R (2002). Amniotic fluid and fetal urinary
responses to severe placental insufficiency in sheep. American Journal
of Obstetrics and Gynaecology May 186:1076-1084.
- Lackman, F., Capewell, V., Richardson, B.S., daSilva, O., Gagnon, R
(2001). The Risk of Spontaneous Preterm Delivery and Perinatal Mortality
in Relation to Size at Birth using Fetal Versus Neonatal Growth Standards.
American Journal of Obstetrics and Gynecology 184:946-953.
- Gagnon R (1997). Can fetal heart rate monitoring ultimately become
a useful tool in obstetrical practice? Journal of the Society of Obstetricians
and Gynaecologists of Canada 19:1385-1391.
- Gagnon R, Murotsuki J, Challis JRG, Fraher L, Richardson BS (1997).
Fetal sheep endocrine responses to sustained hypoxemic stress after chronic
fetal placental embolization. Amer J Physiol: Endo & Metab 272:E817-823.
- Murotsuki J, Gagnon R, Matthews SG, Challis JRG (1996). Effects of
long-term hypoxemia on pituitary-adrenal function in fetal sheep. Amer
J Physiol: Endo & Metab 271:E678-685.
- Gagnon R, Johnston L, Murotsuki J (1996). Fetal placental embolization
in the late gestation ovine fetus: alterations in umbilical blood flow
and fetal heart rate patterns. Amer J Ob Gyn 175:63-72.
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