Dr. Doris E. Yuen, MD, PhD, FAAP, FRCPC


Children’s Health Research Institute
Scientist, Fetal and Newborn Health Program


Lawson Health Research Institute
Scientist, Children’s Health Research Institute


Children’s Hospital of Western Ontario
Postgraduate Education Director, Neonatal-Perinatal Medicine Fellowship Program
Attending Neonatologist, Neonatal Intensive Care Unit


University of Western Ontario
Associate Professor, Department of Paediatrics


Contact Information
Tel: (519) 685-8500 Ext. 64404
Fax: (519) 646-6123
E-mail: dyuen2@uwo.ca


Brief Biography

Dr. Yuen received her PhD in Nutritional Sciences from the University of Guelph in 1987 and her medical degree from the University of British Columbia in 1988. She continued her training in Paediatrics and Neonatology at the Hospital for Sick Children in Toronto, and completed a Research Fellowship in Neonatology at the Children’s Hospital of Eastern Ontario in Ottawa. She has received specialist certification in Pediatrics in the United States (American Boards) as well as from the Royal College of Physicians and Surgeons of Canada.


Dr. Yuen became an Associate Professor in the Department of Paediatrics at The University of Western Ontario in 2002 and is also a Faculty Member of the Division of Neonatal-Perinatal Medicine at St. Joseph’s Health Care London. She was appointed as the Postgraduate Education Director of the Neonatal-Perinatal Medicine Fellowship Program in 2004.


Research Interest

• Gastrointestinal wound healing
• Growth Factors
• Neonatal Gastrointestinal Imaging
• Neonatal Nutrition


Research Activities

Dr. Yuen's research is in the field of neonatal gastroenterology and nutrition. She has developed models for neonatal gastrointestinal injury in experimental animals (piglets and rodents) for evaluating (1) the role of growth factors and extracellular matrix proteins in gut wound healing and (2) the role of vitamin A in the prevention of neonatal gut injury. Her clinical research is focused on (1) investigating the efficacy of vitamin A for the prevention of neonatal gut injury, (2) development of non-invasive methods of assessing function of the premature infant gut and (3) development of evidence-based neonatal nutrition practice guidelines.


Publications

  1. Moher, D., Lewin, G., Schachter, H.M., Yuen, D. et al. (2005). Effects of omega-3 fatty acids on child and maternal health. Agency for Healthcare Research and Quality, publication number 05-E025-2:1-429.
  2. Yuen, D.E., Stratford, A. (2004). Vitamin A activation of transforming growth factor-beta1 enhances porcine ileum wound healing in vitro. Ped Res 55: 935-939.
  3. Yuen, D.E., Leahy, MF and Kao, RLC (2002). S.C. Retinyl Palmitate Accelerates Healing of Intestinal Perforations in a Rat Model. Toronto Critical Care Medicine Symposium.
  4. Yuen, D.E. and Al-Saied, G. (2000). Attenuation of Intestinal Injury with Retinyl Palmitate in a Piglet Model for Necrotizing Enterocolitis, Ped Res 47(4):441a.
  5. Yuen, D.E. (1999). Current Approaches to Evidence-Based Practice. Proceedings of the 108th Ross Conference, Human Milk for Very Low Birthweight Infants, Ross Products Division, Columbus, Ohio, pp.15-25.
  6. Bellemare, S. and Yuen, D.E. (1999). Better Strategies for Approaching Parents about Clinical Trials Involving Neonates. Pedatr Child Health 4(suppl B): 54B.
  7. Yuen, D.E. (1998). Feeding Premature Infants After Hospital Discharge. Can J Ped Health, 3(5):307-308.
  8. Yuen, D.E, (1997). Vitamin and Mineral Supplement Needs of Preterm Infants. Can J Ped Health 2(4):257-8.
  9. Yuen, D.E. and Krantis, A. (1997). Intravenous Transforming Growth Factor-ß1 (TGF-ß1) Attenuated Intestinal Injury in a Porcine Model for Necrotizing Enterocolitis (NEC). Ped Res 41(4 pt 2):188A.
  10. Orovec, N.M. and Yuen D.E. (1996). Early Enteral Feeding of Very Low Birthweight (VLBW) Infants Increases the Risk for Necrotizing Enterocolitis. Ped Res 39(4, pt 2): 225A .
  11. Yuen, D.E., Sne, N. and Krantis, A. (1996). Growth Factor Modulation of Extracellular Matrix Protein Expression During Intestinal Wound Healing. Can J Gastro 10(suppl.).