CHRI Seminar Series
Children's Health Research Institute is pleased to present:
Charles Graham, PhD
Professor and Head, Department of Anatomy and Cell Biology, Queen's University
Title: "Role of abnormal placentation in the pathophysiology of pre-eclampsia"
Date: October 31, 2007
Time: 4:00 pm
Location: Thompson Amphitheatre, Ivey Institute, London
Health Sciences Centre – Victoria Hospital
Research Interests:
Dr. Graham’s research focuses on two general areas: the biology of the human placenta and cancer progression. A specific objective of Dr. Graham's research is to learn how the uterine microenvironment regulates trophoblast invasion and remodeling of the spiral arterioles in the first half of pregnancy.
Bonnie Deroo, PhD
Scientist, Molecular Genetics Program, Children's Health Research Institute
Assistant Professor, Department of Biochemistry, The University of Western Ontario
Title: "Estrogen receptor beta in the ovary: a role in follicle stimulating hormone-mediated cAMP synthesis"
Date: November 7, 2007
Time: 4:00 pm
Location: Thompson Amphitheatre, Ivey Institute, London
Health Sciences Centre – Victoria Hospital
Research Interests:
Infertility affects one in six Canadian couples, and in many cases is due to female infertility causes by infrequent or no ovulation. The goal of Dr. Deroo's lab is to understand how estrogen regulates ovulation by studying knockout mice lacking the gene for estrogen receptor beta, a transcription factor which is activated by estrogen. ERbeta-null mice ovulate less frequently and produce smaller litters than wildtype mice, and their goal is to understand what role ERbeta plays in normal ovulation to better understand causes of infertility in women.
David Hess, PhD
Assistant Professor, Department of Physiology and Pharmacology, The University of Western Ontario
Scientist, Vascular Biology Research Group, Krembil Centre for Stem Cell Biology, Robarts Research Institute
Title: "Segregation of human bone marrow-derived progenitor cell lineages based on aldehyde dehydrogenase activity: Implications for beta-cell and vascular regeneration"
Date: December 5, 2007
Time: 4:00 pm
Location: Thompson Amphitheatre, Ivey Institute, London
Health Sciences Centre – Victoria Hospital
Research Interests:
Dr. Hess is investigating the mechanisms by which distinct stem cell subsets co-ordinate complex biological processes including hematopoiesis, angiogenesis, and tissue regeneration.
Stephen Konieczny, PhD
Professor, Department of Biological Sciences, Purdue University
Title: "Development and Disease - Cellular and Molecular Plasticity in the Pancreas"
Date: January 23, 2008
Time: 4:00 pm
Location: Thompson Amphitheatre, Ivey Institute, London
Health Sciences Centre – Victoria Hospital
Research Interests:
The research in Dr. Konieczny's laboratory involves defining the molecular mechanisms that regulate gene expression in pancreatic and mammary gland epithelial cells during development and in cases of tumor initiation and progression.
Peter Rosenbaum, BSc, MD, FRCPC
Canada Research Chair in Childhood Disability Research, Dissemination & Mentoring
Professor, Department of Paediatrics
Co-Director, CanChild Centre for Childhood Disability Research
McMaster University
Title: "Why there has never been a better time to be in Developmental Paediatrics"
Date: February 13, 2008
Time: 4:00 pm
Location: Thompson Amphitheatre, Ivey Institute, London
Health Sciences Centre – Victoria Hospital
Research Interests:
Dr. Rosenbaum is a Developmental Paediatrician and researcher with special interests in childhood disability. His research areas include: family-centered service; the natural history and prognosis of children with cerebral palsy; measurement and classification of functional status of children with disabilities; and knowledge translation.
Cecilia Moens, PhD
Associate Member, Division of Basic Sciences, Fred Hutchinson Cancer Research Center
Investigator, Howard Hughes Medical Institute
Title: Organizing the Hindbrain Neuroepithelium: The Challenges and Rewards of Segmentation"
Date: April 16, 2008
Time: 4:00 pm
Location: Thompson Amphitheatre, Ivey Institute, London
Health Sciences Centre – Victoria Hospital
Research Interests:
Dr. Moens' research looks at three fundamental questions in developmental biology. The first is how an apparently homogeneous epithelium becomes patterned along its anterior-posterior axis, the second is how morphological boundaries form between groups of cells with different identities, and the third is how cells move in a directed way through a complex patterned environment.
Lee Adamson, PhD
Senior Investigator, Samuel Lunenfeld Research Institute
Title: TBA
Date: May 21, 2008
Time: 4:00 pm
Location: Thompson Amphitheatre, Ivey Institute, London
Health Sciences Centre – Victoria Hospital
Research Interests:
Dr. Adamson's research focuses on four areas: 1) cardiovascular and placental physiology during pregnancy; 2) high resolution ultrasound imaging and Doppler assessment in mice; 3) evaluation of cardiovascular function in vivo in mice during pre- and postnatal development; 4) physiological testing of mutant mice generated by random mutagenesis or other methods
